genetic mutation

noun

plural genetic mutations
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Lacking working copies of the p53 gene, cells can begin to divide without check, though several other genetic mutations are thought to be needed to foster a full-blown malignancy.Natalie Angier

Examples of genetic mutation in a Sentence

Recent Examples on the Web Checking for genetic mutation would be the first step for the treatment. Se Eun Gong, NPR, 15 Sep. 2024 However, some research has found that AFib can sometimes be caused by genetic mutations that affect the heart's electrical system. Angela Ryan Lee, Health, 6 Sep. 2024 In fact, the most common type of hemochromatosis is hereditary hemochromatosis, which occurs due to a genetic mutation. Sarah Jividen, Health, 12 Sep. 2024 Interestingly and maybe worryingly, while most genetic mutations have no effect at all, some can cause viruses to become deadlier or more effective at spreading. Jess Craig, Vox, 15 Aug. 2024 See all Example Sentences for genetic mutation 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'genetic mutation.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1915, in the meaning defined above

Time Traveler
The first known use of genetic mutation was in 1915

Dictionary Entries Near genetic mutation

Cite this Entry

“Genetic mutation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genetic%20mutation. Accessed 2 Oct. 2024.

Medical Definition

genetic mutation

noun
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Gaucher's disease results from one of many genetic mutations that can either slow or prevent the breakdown of certain glycolipids, which accumulate in storage vesicles and eventually kill cells.Joseph Alper
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